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Journal of Biomedical Optics • Open Access • new

Deep convolutional neural networks for classifying head and neck cancer using hyperspectral imaging
Author(s): Martin Halicek; Guolan Lu; James V. Little; Xu Wang; Mihir Patel; Christopher C. Griffith; Mark W. El-Deiry; Amy Y. Chen; Baowei Fei

Paper Abstract

Surgical cancer resection requires an accurate and timely diagnosis of the cancer margins in order to achieve successful patient remission. Hyperspectral imaging (HSI) has emerged as a useful, noncontact technique for acquiring spectral and optical properties of tissue. A convolutional neural network (CNN) classifier is developed to classify excised, squamous-cell carcinoma, thyroid cancer, and normal head and neck tissue samples using HSI. The CNN classification was validated by the manual annotation of a pathologist specialized in head and neck cancer. The preliminary results of 50 patients indicate the potential of HSI and deep learning for automatic tissue-labeling of surgical specimens of head and neck patients.

Paper Details

Date Published: 24 June 2017
PDF: 4 pages
J. Biomed. Opt. 22(6) 060503 doi: 10.1117/1.JBO.22.6.060503
Published in: Journal of Biomedical Optics Volume 22, Issue 6
Show Author Affiliations
Martin Halicek, Georgia Institute of Technology (United States)
Medical College of Georgia (United States)
Emory Univ. (United States)
Guolan Lu, Georgia Institute of Technolog (United States)
Emory Univ. (United States)
James V. Little, Emory Univ. School of Medicine (United States)
Xu Wang, Emory Univ. School of Medicine (United States)
Mihir Patel, Emory Univ. School of Medicine (United States)
Winship Cancer Institute of Emory Univ. (United States)
Christopher C. Griffith, Emory University School of Medicine (United States)
Mark W. El-Deiry, Emory Univ. School of Medicine (United States)
Winship Cancer Institute of Emory Univ. (United States)
Amy Y. Chen, Emory Univ. School of Medicine (United States)
Winship Cancer Institute of Emory Univ. (United States)
Baowei Fei, Georgia Institute of Technology and Emory University (United States)
Winship Cancer Institute of Emory Univ. (United States)
Emory Univ. (United States)


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