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Journal of Biomedical Optics • new

Simulated altitude exposure assessment by hyperspectral imaging
Author(s): Mihaela Antonina Calin; Adrian Macovei; Sorin Miclos; Sorin Viorel Parasca; Roxana Savastru; Razvan Hristea
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Paper Abstract

Testing the human body’s reaction to hypoxia (including the one generated by high altitude) is important in aeronautic medicine. This paper presents a method of monitoring blood oxygenation during experimental hypoxia using hyperspectral imaging (HSI) and a spectral unmixing model based on a modified Beer–Lambert law. A total of 20 healthy volunteers (males) aged 25 to 60 years were included in this study. A line-scan HSI system was used to acquire images of the faces of the subjects. The method generated oxyhemoglobin and deoxyhemoglobin distribution maps from the foreheads of the subjects at 5 and 10 min of hypoxia and after recovery in a high oxygen breathing mixture. The method also generated oxygen saturation maps that were validated using pulse oximetry. An interesting pattern of desaturation on the forehead was discovered during the study, showing one of the advantages of using HSI for skin oxygenation monitoring in hypoxic conditions. This could bring new insight into the physiological response to high altitude and may become a step forward in air crew testing.

Paper Details

Date Published: 31 May 2017
PDF: 8 pages
J. Biomed. Opt. 22(5) 056012 doi: 10.1117/1.JBO.22.5.056012
Published in: Journal of Biomedical Optics Volume 22, Issue 5
Show Author Affiliations
Mihaela Antonina Calin, National Institute of Research and Development for Optoelectronics (Romania)
Adrian Macovei, National Institute of Aeronautical and Space Medicine, “Gen. Dr. Aviator Victor Anastasiu” (Romania)
Sorin Miclos, National Institute of Research and Development for Optoelectronics (Romania)
Sorin Viorel Parasca, Emergency Clinical Hospital for Plastic, Reconstructive Surgery and Burns (Romania)
"Carol Davila" Univ. of Medicine and Pharmacy (Romania)
Roxana Savastru, National Institute of Research and Development for Optoelectronics (Romania)
Razvan Hristea, National Institute of Aeronautical and Space Medicine, “Gen. Dr. Aviator Victor Anastasiu” (Romania)


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