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Journal of Biomedical Optics

Direct numerical simulation of the initial stage of a thermally induced microcavitation in a water-rich biotissue triggered by a nanosecond pulsed laser
Author(s): Sy-Bor Wen; Kevin J. Ly; Arun Bhaskar; Morgan S. Schmidt; Robert J. Thomas
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Paper Abstract

A numerical analysis capable of describing the early stage of a thermal microcavitation process in a water-rich biotissue without avalanche breakdown was developed. The analysis successfully reproduced the laser-induced heating, vapor bubble formation, bubble expansion, and shockwave propagation inside a water-rich biotissue during a thermal microcavitation process. Based on the analysis, it was determined that the evolution of the temperature, pressure, and laser-induced shockwave is dependent on the incident laser energy and laser pulse width. On the other hand, the early stage dynamics of the microcavitation process showed little dependence on the elastic modulus of the biotissue for the laser and tissue conditions studied.

Paper Details

Date Published: 3 May 2017
PDF: 12 pages
J. Biomed. Opt. 22(5) 056002 doi: 10.1117/1.JBO.22.5.056002
Published in: Journal of Biomedical Optics Volume 22, Issue 5
Show Author Affiliations
Sy-Bor Wen, Texas A&M Univ. (United States)
Kevin J. Ly, Texas A&M Univ. (United States)
Arun Bhaskar, Texas A&M Univ. (United States)
Morgan S. Schmidt, 711th Human Effectiveness Directorate (United States)
Robert J. Thomas, 711th Human Effectiveness Directorate (United States)


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