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Journal of Biomedical Optics • Open Access

Design of a multifiber light delivery system for photoacoustic-guided surgery
Author(s): Blackberrie Eddins; Muyinatu A. Lediju Bell

Paper Abstract

This work explores light delivery optimization for photoacoustic-guided minimally invasive surgeries, such as the endonasal transsphenoidal approach. Monte Carlo simulations were employed to study three-dimensional light propagation in tissue, comprising one or two 4-mm diameter arteries located 3 mm below bone, an absorbing metallic drill contacting the bone surface, and a single light source placed next to the 2.4-mm diameter drill shaft with a 2.9-mm diameter spherical drill tip. The optimal fiber distance from the drill shaft was determined from the maximum normalized fluence to the underlying artery. Using this optimal fiber-to-drill shaft distance, Zemax simulations were employed to propagate Gaussian beams through one or more 600 micron-core diameter optical fibers for detection on the bone surface. When the number of equally spaced fibers surrounding the drill increased, a single merged optical profile formed with seven or more fibers, determined by thresholding the resulting light profile images at 1 / e times the maximum intensity. We used these simulations to inform design requirements, build a one to seven multifiber light delivery prototype to surround a surgical drill, and demonstrate its ability to simultaneously visualize the tool tip and blood vessel targets in the absence and presence of bone. The results and methodology are generalizable to multiple interventional photoacoustic applications.

Paper Details

Date Published: 13 January 2017
PDF: 11 pages
J. Biomed. Opt. 22(4) 041011 doi: 10.1117/1.JBO.22.4.041011
Published in: Journal of Biomedical Optics Volume 22, Issue 4
Show Author Affiliations
Blackberrie Eddins, Johns Hopkins Univ. (United States)
Muyinatu A. Lediju Bell, Johns Hopkins Univ. (United States)


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