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Journal of Biomedical Optics

Label-free high-throughput detection and quantification of circulating melanoma tumor cell clusters by linear-array-based photoacoustic tomography
Author(s): Pengfei Hai; Yong Zhou; Ruiying Zhang; Jun Ma; Yang Li; Jin-Yu Shao; Lihong V. Wang
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Paper Abstract

Circulating tumor cell (CTC) clusters, arising from multicellular groupings in a primary tumor, greatly elevate the metastatic potential of cancer compared with single CTCs. High-throughput detection and quantification of CTC clusters are important for understanding the tumor metastatic process and improving cancer therapy. Here, we applied a linear-array-based photoacoustic tomography (LA-PAT) system and improved the image reconstruction for label-free high-throughput CTC cluster detection and quantification

Paper Details

Date Published: 10 November 2016
PDF: 6 pages
J. Biomed. Opt. 22(4) 041004 doi: 10.1117/1.JBO.22.4.041004
Published in: Journal of Biomedical Optics Volume 22, Issue 4
Show Author Affiliations
Pengfei Hai, Washington Univ. in St. Louis (United States)
Yong Zhou, Washington Univ. in St. Louis (United States)
Ruiying Zhang, Washington Univ. in St. Louis (United States)
Jun Ma, Washington Univ. in St. Louis (United States)
Yang Li, Washington Univ. in St. Louis (United States)
Jin-Yu Shao, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


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