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Journal of Biomedical Optics

Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration
Author(s): Masatoshi Ando; Andrea G. Ferreira-Zandoná; George J. Eckert; Domenick T. Zero; George K. Stookey
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Paper Abstract

This study aimed to evaluate the ability of quantitative light-induced fluorescence (QLF) to assess caries lesion activity using visual examination (VE) as the gold standard. Twenty-four visible white spot lesions on buccal surfaces were examined from 23 children, ages 9 to 14 years. At baseline, the surface was hydrated with water, and thereafter, it was dehydrated with continuous compressed air during image acquisition. QLF images were acquired at 0 (baseline), 5, and 15 s. QLF variables [ QLF V : fluorescence loss ( Δ F ), lesion size (S), Δ Q : Δ F × S ] was recorded. Changes-in- QLF V per second ( Δ QLF V ) were determined: Δ QLF V = ( QLF VN QLF V Baseline ) / N , where N indicates dehydration time. One experienced dentist conducted VE independently using a dental unit’s light, compressed air, and explorer.

Paper Details

Date Published: 10 March 2017
PDF: 6 pages
J. Biomed. Opt. 22(3) 035005 doi: 10.1117/1.JBO.22.3.035005
Published in: Journal of Biomedical Optics Volume 22, Issue 3
Show Author Affiliations
Masatoshi Ando, Indiana Univ. School of Dentistry (United States)
Andrea G. Ferreira-Zandoná, The Univ. of North Carolina at Chapel Hill (United States)
George J. Eckert, Indiana Univ. (United States)
Domenick T. Zero, Indiana Univ. School of Dentistry (United States)
George K. Stookey, Therametric Technologies, Inc. (United States)

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