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Journal of Biomedical Optics • Open Access • new

Compressed single pixel imaging in the spatial frequency domain
Author(s): Mohammad Torabzadeh; Il-Yong Park; Randy A. Bartels; Anthony J. Durkin; Bruce J. Tromberg

Paper Abstract

We have developed compressed sensing single pixel spatial frequency domain imaging (cs-SFDI) to characterize tissue optical properties over a wide field of view ( 35    mm × 35    mm ) using multiple near-infrared (NIR) wavelengths simultaneously. Our approach takes advantage of the relatively sparse spatial content required for mapping tissue optical properties at length scales comparable to the transport scattering length in tissue ( l tr 1    mm ) and the high bandwidth available for spectral encoding using a single-element detector. cs-SFDI recovered absorption ( μ a ) and reduced scattering ( μ s ) coefficients of a tissue phantom at three NIR wavelengths (660, 850, and 940 nm) within 7.6% and 4.3% of absolute values determined using camera-based SFDI, respectively. These results suggest that cs-SFDI can be developed as a multi- and hyperspectral imaging modality for quantitative, dynamic imaging of tissue optical and physiological properties.

Paper Details

Date Published: 16 March 2017
PDF: 4 pages
J. Biomed. Opt. 22(3) 030501 doi: 10.1117/1.JBO.22.3.030501
Published in: Journal of Biomedical Optics Volume 22, Issue 3
Show Author Affiliations
Mohammad Torabzadeh, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Il-Yong Park, Dankook Univ. (Republic of Korea)
Randy A. Bartels, Colorado State Univ. (United States)
Anthony J. Durkin, Beckman Laser Institute and Medical Clinic (United States)
Bruce J. Tromberg, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)

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