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Journal of Biomedical Optics

Optical properties of the human round window membrane
Author(s): Martin Höhl; Daphne DeTemple; Stefan Lyutenski; Georg Leuteritz; Arthur Varkentin; Heike Andrea Schmitt; Thomas Lenarz; Bernhard Roth; Merve Meinhardt-Wollweber; Uwe Morgner
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Paper Abstract

Optical techniques are effective tools for diagnostic applications in medicine and are particularly attractive for the noninvasive analysis of biological tissues and fluids in vivo. Noninvasive examinations of substances via a fiber optic probe need to consider the optical properties of biological tissues obstructing the optical path. This applies to the analysis of the human perilymph, which is located behind the round window membrane. The composition of this inner ear liquid is directly correlated to inner ear hearing loss. In this work, experimental methods for studying the optical properties of the human round window membrane ex vivo are presented. For the first time, a comprehensive investigation of this tissue is performed, including optical transmission, forward scattering, and Raman scattering. The results obtained suggest the application of visible wavelengths ( > 400    nm ) for investigating the perilymph behind the round window membrane in future.

Paper Details

Date Published: 27 October 2017
PDF: 7 pages
J. Biomed. Opt. 22(10) 105007 doi: 10.1117/1.JBO.22.10.105007
Published in: Journal of Biomedical Optics Volume 22, Issue 10
Show Author Affiliations
Martin Höhl, Leibniz Univ. Hannover (Germany)
Exzellenzcluster Hearing4all (Germany)
Daphne DeTemple, Leibniz Univ. Hannover (Germany)
Exzellenzcluster Hearing4all (Germany)
Stefan Lyutenski, Medizinische Hochschule Hannover (Germany)
Georg Leuteritz, Leibniz Univ. Hannover (Germany)
Arthur Varkentin, Leibniz Univ. Hannover (Germany)
Heike Andrea Schmitt, Exzellenzcluster Hearing4all (Germany)
Medizinische Hochschule Hannover (Germany)
Thomas Lenarz, Exzellenzcluster Hearing4all (Germany)
Medizinische Hochschule Hannover (Germany)
Bernhard Roth, Leibniz Univ. Hannover (Germany)
Merve Meinhardt-Wollweber, Leibniz Univ. Hannover (Germany)
Hannoversches Zentrum für Optische Technologien (Germany)
Exzellenzcluster Hearing4all (Germany)
Uwe Morgner, Leibniz Univ. Hannover (Germany)
Exzellenzcluster Hearing4all (Germany)


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