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Journal of Biomedical Optics

Lorentz force optical coherence elastography
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Paper Abstract

Quantifying tissue biomechanical properties can assist in detection of abnormalities and monitoring disease progression and/or response to a therapy. Optical coherence elastography (OCE) has emerged as a promising technique for noninvasively characterizing tissue biomechanical properties. Several mechanical loading techniques have been proposed to induce static or transient deformations in tissues, but each has its own areas of applications and limitations. This study demonstrates the combination of Lorentz force excitation and phase-sensitive OCE at ∼1.5  million A-lines per second to quantify the elasticity of tissue by directly imaging Lorentz force-induced elastic waves. This method of tissue excitation opens the possibility of a wide range of investigations using tissue biocurrents and conductivity for biomechanical analysis.

Paper Details

Date Published: 12 September 2016
PDF: 4 pages
J. Biomed. Opt. 21(9) 090502 doi: 10.1117/1.JBO.21.9.090502
Published in: Journal of Biomedical Optics Volume 21, Issue 9
Show Author Affiliations
Chen Wu, Univ. of Houston (United States)
Manmohan Singh, Univ. of Houston (United States)
Zhaolong Han, Univ. of Houston (United States)
Raksha Raghunathan, Univ. of Houston (United States)
Chih-Hao Liu, Univ. of Houston (United States)
Jiasong Li, Univ. of Houston (United States)
Alexander Schill, Univ. of Houston (United States)
Kirill V. Larin, Univ. of Houston (United States)
National Research Tomsk State Univ. (Russia)
Baylor College of Medicine (United States)


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