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Journal of Biomedical Optics • new

Fast direct reconstruction strategy of dynamic fluorescence molecular tomography using graphics processing units
Author(s): Maomao Chen; Jiulou Zhang; Chuangjian Cai; Yang Gao; Jianwen Luo
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Paper Abstract

Dynamic fluorescence molecular tomography (DFMT) is a valuable method to evaluate the metabolic process of contrast agents in different organs in vivo, and direct reconstruction methods can improve the temporal resolution of DFMT. However, challenges still remain due to the large time consumption of the direct reconstruction methods. An acceleration strategy using graphics processing units (GPU) is presented. The procedure of conjugate gradient optimization in the direct reconstruction method is programmed using the compute unified device architecture and then accelerated on GPU. Numerical simulations and in vivo experiments are performed to validate the feasibility of the strategy. The results demonstrate that, compared with the traditional method, the proposed strategy can reduce the time consumption by ∼90% without a degradation of quality.

Paper Details

Date Published: 14 June 2016
PDF: 11 pages
J. Biomed. Opt. 21(6) 066010 doi: 10.1117/1.JBO.21.6.066010
Published in: Journal of Biomedical Optics Volume 21, Issue 6
Show Author Affiliations
Maomao Chen, Tsinghua Univ. (China)
Jiulou Zhang, Tsinghua Univ. (China)
Chuangjian Cai, Tsinghua Univ. (China)
Yang Gao, Tsinghua Univ. (China)
Jianwen Luo, Tsinghua Univ. School of Medicine (China)


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