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Journal of Biomedical Optics • Open Access

Lensless two-photon imaging through a multicore fiber with coherence-gated digital phase conjugation
Author(s): Donald B. Conkey; Nicolino Stasio; Edgar E. Morales-Delgado; Marilisa Romito; Christophe Moser; Demetri Psaltis

Paper Abstract

We performed near-diffraction limited two-photon fluorescence (TPF) imaging through a lensless, multicore-fiber (MCF) endoscope utilizing digital phase conjugation. The phase conjugation technique is compatible with commercially available MCFs with high core density. We demonstrate focusing of ultrashort pulses through an MCF and show that the method allows for resolution that is not limited by the MCF core spacing. We constructed TPF images of fluorescent beads and cells by digital scanning of the phase-conjugated focus on the target object and collection of the emitted fluorescence through the MCF.

Paper Details

Date Published: 18 April 2016
PDF: 9 pages
J. Biomed. Opt. 21(4) 045002 doi: 10.1117/1.JBO.21.4.045002
Published in: Journal of Biomedical Optics Volume 21, Issue 4
Show Author Affiliations
Donald B. Conkey, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Nicolino Stasio, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Edgar E. Morales-Delgado, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Marilisa Romito, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Christophe Moser, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Demetri Psaltis, Ecole Polytechnique Fédérale de Lausanne (Switzerland)


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