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Journal of Biomedical Optics

Delay-multiply-and-sum-based synthetic aperture focusing in photoacoustic microscopy
Author(s): Jongin Park; Seungwan Jeon; Jing Meng; Liang Song; Jin S. Lee; Chulhong Kim
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Paper Abstract

We propose an improved version of a synthetic aperture focusing technique (SAFT) based on a delay-multiply-and-sum algorithm for acoustic-resolution photoacoustic microscopy (AR-PAM). In this method, the photoacoustic (PA) signals from multiple scan-lines are combinatorially coupled, multiplied, and then summed. This process can be considered a correlation operation of the PA signals in each scan-line, so the spatial coherent information between the PA signals can be efficiently extracted. By applying this method in conventional AR-PAM, lateral resolution and signal-to-noise ratio in out-of-focus regions are much improved compared with those estimated from the previously developed SAFT, respectively, thereby achieving the extension of the imaging focal region. Our phantom and <italic<in vivo</italic< imaging experiments prove the validity of our proposed method.

Paper Details

Date Published: 28 March 2016
PDF: 10 pages
J. Biomed. Opt. 21(3) 036010 doi: 10.1117/1.JBO.21.3.036010
Published in: Journal of Biomedical Optics Volume 21, Issue 3
Show Author Affiliations
Jongin Park, Pohang Univ. of Science and Technology (Republic of Korea)
Seungwan Jeon, Pohang Univ. of Science and Technology (Republic of Korea)
Jing Meng, Qufu Normal Univ. (China)
Liang Song, Shenzhen Institute of Advanced Technology (China)
Jin S. Lee, Pohang Univ. of Science and Technology (Republic of Korea)
Chulhong Kim, Pohang Univ. of Science and Technology (Republic of Korea)

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