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Journal of Biomedical Optics • Open Access

Colored lenses suppress blue light-emitting diode light-induced damage in photoreceptor-derived cells
Author(s): Kaho Hiromoto; Yoshiki Kuse; Kazuhiro Tsuruma; Nobuyuki Tadokoro; Nobuyuki Kaneko; Masamitsu Shimazawa; Hideaki Hara

Paper Abstract

Blue light-emitting diodes (LEDs) in liquid crystal displays emit high levels of blue light, exposure to which is harmful to the retina. Here, we investigated the protective effects of colored lenses in blue LED light-induced damage to 661W photoreceptor-derived cells. We used eight kinds of colored lenses and one lens that reflects blue light. Moreover, we evaluated the relationship between the protective effects of the lens and the transmittance of lens at 464 nm. Lenses of six colors, except for the SY, PN, and reflective coating lenses, strongly decreased the reduction in cell damage induced by blue LED light exposure. The deep yellow lens showed the most protective effect from all the lenses, but the reflective coating lens and pink lens did not show any effects on photoreceptor-derived cell damage. Moreover, these results were correlated with the lens transmittance of blue LED light (464 nm). These results suggest that lenses of various colors, especially deep yellow lenses, may protect retinal photoreceptor cells from blue LED light in proportion to the transmittance for the wavelength of blue LED and the suppression of reactive oxygen species production and cell damage.

Paper Details

Date Published: 23 March 2016
PDF: 10 pages
J. Biomed. Opt. 21(3) 035004 doi: 10.1117/1.JBO.21.3.035004
Published in: Journal of Biomedical Optics Volume 21, Issue 3
Show Author Affiliations
Kaho Hiromoto, Gifu Pharmaceutical Univ. (Japan)
Yoshiki Kuse, Gifu Pharmaceutical Univ. (Japan)
Kazuhiro Tsuruma, Gifu Pharmaceutical Univ. (Japan)
Nobuyuki Tadokoro, HOYA Corp. (Japan)
Nobuyuki Kaneko, HOYA Corp. (Japan)
Masamitsu Shimazawa, Gifu Pharmaceutical Univ. (Japan)
Hideaki Hara, Gifu Pharmaceutical Univ. (Japan)

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