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Journal of Biomedical Optics • Open Access

Multimodality Raman and photoacoustic imaging of surface-enhanced-Raman-scattering-targeted tumor cells
Author(s): Wei Shi; Robert J. Paproski; Peng Shao; Alexander Forbrich; John D. Lewis; Roger J. Zemp

Paper Abstract

A multimodality Raman and photoacoustic imaging system is presented. This system has ultralow background and can detect tumor cells labeled with modified surface-enhanced-Raman-scattering (SERS) nanoparticles <italic<in vivo</italic<. Photoacoustic imaging provides microvascular context and can potentially be used to guide magnetic trapping of circulating tumor cells for SERS detection in animal models.

Paper Details

Date Published: 25 February 2016
PDF: 4 pages
J. Biomed. Opt. 21(2) 020503 doi: 10.1117/1.JBO.21.2.020503
Published in: Journal of Biomedical Optics Volume 21, Issue 2
Show Author Affiliations
Wei Shi, Univ. of Alberta (Canada)
Robert J. Paproski, Univ. of Alberta (Canada)
Peng Shao, Univ. of Alberta (Canada)
Alexander Forbrich, Univ. of Alberta (Canada)
John D. Lewis, Univ. of Alberta (Canada)
Roger J. Zemp, Univ. of Alberta (Canada)

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