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Journal of Biomedical Optics • Open Access

Analysis and compensation for the effect of the catheter position on image intensities in intravascular optical coherence tomography
Author(s): Shengnan Liu; Jeroen Eggermont; Ron Wolterbeek; Alexander Broersen; Carol A. G. R. Busk; Helle Precht; Boudewijn P. F. Lelieveldt; Jouke Dijkstra

Paper Abstract

Intravascular optical coherence tomography (IVOCT) is an imaging technique that is used to analyze the underlying cause of cardiovascular disease. Because a catheter is used during imaging, the intensities can be affected by the catheter position. This work aims to analyze the effect of the catheter position on IVOCT image intensities and to propose a compensation method to minimize this effect in order to improve the visualization and the automatic analysis of IVOCT images. The effect of catheter position is modeled with respect to the distance between the catheter and the arterial wall (distance-dependent factor) and the incident angle onto the arterial wall (angle-dependent factor). A light transmission model incorporating both factors is introduced. On the basis of this model, the interaction effect of both factors is estimated with a hierarchical multivariant linear regression model. Statistical analysis shows that IVOCT intensities are significantly affected by both factors with p<0.001, as either aspect increases the intensity decreases. This effect differs for different pullbacks. The regression results were used to compensate for this effect. Experiments show that the proposed compensation method can improve the performance of the automatic bioresorbable vascular scaffold strut detection.

Paper Details

Date Published: 7 December 2016
PDF: 9 pages
J. Biomed. Opt. 21(12) 126005 doi: 10.1117/1.JBO.21.12.126005
Published in: Journal of Biomedical Optics Volume 21, Issue 12
Show Author Affiliations
Shengnan Liu, Leiden Univ. Medical Ctr. (The Netherlands)
Jeroen Eggermont, Leiden Univ. Medical Ctr. (Netherlands)
Ron Wolterbeek, Leiden Univ. Medical Ctr. (Netherlands)
Alexander Broersen, Leiden Univ. Medical Ctr. (Netherlands)
Carol A. G. R. Busk, Univ. of Southern Denmark (Denmark)
Helle Precht, Univ. College Lillebaelt (Denmark)
Boudewijn P. F. Lelieveldt, Leiden Univ. Medical Ctr. (Netherlands)
Delft Univ. of Technology (Netherlands)
Jouke Dijkstra, Leiden Univ. Medical Ctr. (Netherlands)


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