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Journal of Biomedical Optics • Open Access

Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler
Author(s): Robin Guay-Lord; Xavier Attendu; Kristen L. Lurie; Lucas Majeau; Nicolas Godbout; Audrey K. Bowden; Mathias Strupler; Caroline Boudoux

Paper Abstract

This work demonstrates the combination of optical coherence tomography (OCT) and hyperspectral imaging (HSI) using a double-clad optical fiber coupler. The single-mode core of the fiber is used for OCT imaging, while the inner cladding of the double-clad fiber provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of the sample morphology with OCT, enhanced with complementary molecular information contained in the hyperspectral image. The HSI data can be used to highlight the presence of specific molecules with characteristic absorption peaks or to produce true color images overlaid on the OCT volume for improved tissue identification by the clinician. Such a system could be implemented in a number of clinical endoscopic applications and could improve the current practice in tissue characterization, diagnosis, and surgical guidance.

Paper Details

Date Published: 9 November 2016
PDF: 6 pages
J. Biomed. Opt. 21(11) 116008 doi: 10.1117/1.JBO.21.11.116008
Published in: Journal of Biomedical Optics Volume 21, Issue 11
Show Author Affiliations
Robin Guay-Lord, Ecole Polytechnique de Montréal (Canada)
Xavier Attendu, Ecole Polytechnique de Montréal (Canada)
Kristen L. Lurie, Stanford Univ. (United States)
Lucas Majeau, École Polytechnique de Montreal (Canada)
Nicolas Godbout, Ecole Polytechnique de Montréal (Canada)
Castor Optics (Canada)
Audrey K. Bowden, Stanford Univ. (United States)
Mathias Strupler, Ecole Polytechnique de Montréal (Canada)
Caroline Boudoux, Ecole Polytechnique de Montréal (Canada)
Castor Optics (Canada)

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