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Journal of Biomedical Optics

Comparison of different cutaneous carotenoid sensors and influence of age, skin type, and kinetic changes subsequent to intake of a vegetable extract
Author(s): Martina C. Meinke; Sabine Schanzer; Silke B. Lohan; Ihar Shchatsinin; Maxim E. Darvin; Henning Vollert; Björn Magnussen; Wolfang Köcher; Jürgen Helfmann; Jürgen Lademann
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Paper Abstract

In the last decade, cutaneous carotenoid measurements have become increasingly popular, as carotenoids were found to be a biomarker of nutrition rich in fruits and vegetables, permitting monitoring of the influence of various stress factors. For such measurements, in addition to the specific and selective resonance Raman spectroscopy (RRS), newly developed low expensive small and mobile sensors that are based on spatially resolved reflectance spectroscopy (SRRS) are used for cutaneous carotenoid measurements. Human volunteers of different age exhibiting skin types I to III were investigated using RRS and two SRRS-based sensors to determine the influence of these parameters on the measuring results. In two studies on volunteers of either the same age or skin type, however, the respective other parameter being varied and no significant influences of age or skin type could be detected. Furthermore, the kinetic changes resulting from the intake and discontinued intake of a vegetable extract rich in carotenoids showed a good correlation among the three sensors and with the detected blood carotenoids. This illustrates that the SRRS-based sensors and RRS device provide reliable cutaneous carotenoid values independent of age and skin types I to III of the volunteers.

Paper Details

Date Published: 20 October 2016
PDF: 8 pages
J. Biomed. Opt. 21(10) 107002 doi: 10.1117/1.JBO.21.10.107002
Published in: Journal of Biomedical Optics Volume 21, Issue 10
Show Author Affiliations
Martina C. Meinke, Charité Universitätsmedizin Berlin (Germany)
Sabine Schanzer, Charité Universitätsmedizin Berlin (Germany)
Silke B. Lohan, Charité Universitätsmedizin Berlin (Germany)
Ihar Shchatsinin, Laser- und Medizin-Technologie GmbH, Berlin (Germany)
Maxim E. Darvin, Charité Universitätsmedizin Berlin (Germany)
Henning Vollert, BioActive Food GmbH (Germany)
Björn Magnussen, Opsolution GmbH (Germany)
Wolfang Köcher, Opsolution GmbH (Germany)
Jürgen Helfmann, Laser- und Medizin-Technologie GmbH, Berlin (Germany)
Jürgen Lademann, Charité Universitätsmedizin Berlin (Germany)

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