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Journal of Biomedical Optics • Open Access

Spectral characteristics of caries-related autofluorescence spectra and their use for diagnosis of caries stage
Author(s): Sung-Ae Son; Kyeong-Hoon Jung; Ching-Chang Ko; Yong Hoon Kwon

Paper Abstract

The purpose of the present study was to identify factors useful for diagnosis of the caries stage from laser-induced autofluorescence (AF) spectra. Affected teeth were accurately staged and allocated to four groups: sound, stage II, stage III, or stage IV. A 405-nm laser was used to produce AF spectra. The spectrum factors analyzed were spectrum slope at 550 to 600 nm, spectral area from 500 and 590 nm, and intensity ratio of peaks 625 and 667 nm (625/667  nm). DIAGNOdent was used as control measurement. AF spectra of sound teeth had a peak near 500 nm followed by a smooth decline to 800 nm. As caries progressed, some specimens in stages II to IV showed one or two peak(s) near 625 and 667 nm. Slopes at 550 to 600 nm and areas under the curve at 500 to 590 nm were significantly different (p<0.001) for each stage. Two-peak ratios were also significantly different (p<0.001) except for stage III and stage IV. DIAGNOdent readings for sound and stage II and stage III and IV were not significantly different. Among the studied factors, the spectrum slope at 550 to 600 nm and area under curve at 500 to 590 nm could be useful treatment decision-making tools for carious lesions.

Paper Details

Date Published: 6 January 2016
PDF: 8 pages
J. Biomed. Opt. 21(1) 015001 doi: 10.1117/1.JBO.21.1.015001
Published in: Journal of Biomedical Optics Volume 21, Issue 1
Show Author Affiliations
Sung-Ae Son, Pusan National Univ. (Republic of Korea)
Kyeong-Hoon Jung, Kookmin Univ. (Republic of Korea)
Ching-Chang Ko, The Univ. of North Carolina at Chapel Hill (United States)
Yong Hoon Kwon, Pusan National Univ. (Republic of Korea)

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