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Journal of Biomedical Optics

Efficacy of low-level laser therapy for the treatment of burning mouth syndrome: a randomized, controlled trial
Author(s): Juliana Cassol Spanemberg; José López; Maria Antonia Zancanaro de Figueiredo; Karen Cherubini; Fernanda Salum
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Paper Abstract

The aim of the present study was to assess the effect of low-level laser therapy (LLLT) in the treatment of burning mouth syndrome (BMS). A diode laser was used in 78 BMS patients who were randomly assigned into four groups: IR1W, n=20 (830 nm, 100 mW, 5 J, 176  J/cm2, 50 s, LLLT weekly sessions, 10 sessions); IR3W, n=20 (830 nm, 100 mW, 5 J, 176  J/cm2, 50 s, three LLLT weekly sessions, 9 sessions); red laser, n=19 (685 nm, 35 mW, 2 J, 72  J/cm2, 58 s, three LLLT weekly sessions, 9 sessions); and control-group (CG), n=19. Symptoms were assessed at the end of the treatment and eight weeks later; quality of life related to oral health was assessed using the Oral Health Impact Profile (OHIP-14). Statistical analysis was carried out using repeated measures analysis of variance followed by the posthoc Tukey test. There was significant reduction of the symptoms in all groups at the end of the treatment, which was maintained in the follow-up. The scores of the IR1W and IR3W laser groups differed significantly from those of the CG. There was also a decrease in the OHIP-14 scores in the four groups. The IR3W laser group scores differed significantly from those of the CG. LLLT reduces the symptoms of BMS and may be an alternative therapeutic strategy for the relief of symptoms in patients with BMS.

Paper Details

Date Published: 11 September 2015
PDF: 7 pages
J. Biomed. Opt. 20(9) 098001 doi: 10.1117/1.JBO.20.9.098001
Published in: Journal of Biomedical Optics Volume 20, Issue 9
Show Author Affiliations
Juliana Cassol Spanemberg, Pontifícia Univ. Católica do Rio Grande do Sul (Brazil)
José López, Univ. de Barcelona (Spain)
Maria Antonia Zancanaro de Figueiredo, Pontifícia Univ. Católica do Rio Grande do Sul (Brazil)
Karen Cherubini, Pontifícia Univ. Católica do Rio Grande do Sul (Brazil)
Fernanda Salum, Pontifícia Univ. Católica do Rio Grande do Sul (Brazil)


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