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Journal of Biomedical Optics

Increasing depth penetration in biological tissue imaging using 808-nm excited Nd3+/Yb3+/Er3+-doped upconverting nanoparticles
Author(s): Hugo Söderlund; Monirehalsadat Mousavi; Haichun Liu; Stefan Andersson-Engels
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Paper Abstract

Ytterbium (Yb3+)-sensitized upconverting nanoparticles (UCNPs) are excited at 975 nm causing relatively high absorption in tissue. A new type of UCNPs with neodymium (Nd3+) and Yb3+ codoping is excitable at a 808-nm wavelength. At this wavelength, the tissue absorption is lower. Here we quantify, both experimentally and theoretically, to what extent Nd3+-doped UCNPs will provide an increased signal at larger depths in tissue compared to conventional 975-nm excited UCNPs.

Paper Details

Date Published: 13 August 2015
PDF: 7 pages
J. Biomed. Opt. 20(8) 086008 doi: 10.1117/1.JBO.20.8.086008
Published in: Journal of Biomedical Optics Volume 20, Issue 8
Show Author Affiliations
Hugo Söderlund, Lund Univ. (Sweden)
Monirehalsadat Mousavi, Lund Univ. (Sweden)
Haichun Liu, Lund Univ. (Sweden)
Stefan Andersson-Engels, Lund Univ. (Sweden)

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