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Journal of Biomedical Optics • Open Access

Spatiotemporal correlation of optical coherence tomography in-vivo images of rabbit airway for the diagnosis of edema
Author(s): DongYel Kang; Alex Wang; Veronika Volgger; Zhongping Chen; Brian J. F. Wong

Paper Abstract

Detection of an early stage of subglottic edema is vital for airway management and prevention of stenosis, a life-threatening condition in critically ill neonates. As an observer for the task of diagnosing edema in vivo, we investigated spatiotemporal correlation (STC) of full-range optical coherence tomography (OCT) images acquired in the rabbit airway with experimentally simulated edema. Operating the STC observer on OCT images generates STC coefficients as test statistics for the statistical decision task. Resulting from this, the receiver operating characteristic (ROC) curves for the diagnosis of airway edema with full-range OCT in-vivo images were extracted and areas under ROC curves were calculated. These statistically quantified results demonstrated the potential clinical feasibility of the STC method as a means to identify early airway edema.

Paper Details

Date Published: 29 July 2015
PDF: 7 pages
J. Biomed. Opt. 20(7) 076015 doi: 10.1117/1.JBO.20.7.076015
Published in: Journal of Biomedical Optics Volume 20, Issue 7
Show Author Affiliations
DongYel Kang, Hanbat National Univ. (Republic of Korea)
Alex Wang, Univ. of California, Irvine (United States)
Veronika Volgger, Ludwig-Maximilians-Univ. München (Germany)
Zhongping Chen, Univ. of California, Irvine (United States)
Brian J. F. Wong, Univ. of California, Irvine (United States)

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