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Journal of Biomedical Optics

Development of ultraviolet- and visible-light one-shot spectral domain optical coherence tomography and in situ measurements of human skin
Author(s): Heijiro Hirayama; Sohichiro Nakamura
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Paper Abstract

We have developed ultraviolet (UV)- and visible-light one-shot spectral domain (SD) optical coherence tomography (OCT) that enables in situ imaging of human skin with an arbitrary wavelength in the UV–visible-light region (370–800 nm). We alleviated the computational burden for each color OCT image by physically dispersing the irradiating light with a color filter. The system consists of SD-OCT with multicylindrical lenses; thus, mechanical scanning of the mirror or stage is unnecessary to obtain an OCT image. Therefore, only a few dozens of milliseconds are necessary to obtain single-image data. We acquired OCT images of one subject’s skin in vivo and of a skin excision ex vivo for red (R, 650±20  nm), green (G, 550±20  nm), blue (B, 450±20  nm), and UV (397±5  nm) light. In the visible-light spectrum, R light penetrated the skin and was reflected at a lower depth than G or B light. On the skin excision, we demonstrated that UV light reached the dermal layer. We anticipated that basic knowledge about the spectral properties of human skin in the depth direction could be acquired with this system.

Paper Details

Date Published: 29 July 2015
PDF: 5 pages
J. Biomed. Opt. 20(7) 076014 doi: 10.1117/1.JBO.20.7.076014
Published in: Journal of Biomedical Optics Volume 20, Issue 7
Show Author Affiliations
Heijiro Hirayama, FUJIFILM Corp. (Japan)
Sohichiro Nakamura, FUJIFILM Corp. (Japan)

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