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Journal of Biomedical Optics

In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method
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Paper Abstract

Microvascular network of the retina plays an important role in diagnosis and monitoring of various retinal diseases. We propose a three-dimensional (3-D) segmentation method with intensity-based Doppler variance (IBDV) based on swept-source optical coherence tomography. The automatic 3-D segmentation method is used to obtain seven surfaces of intraretinal layers. The microvascular network of the retina, which is acquired by the IBDV method, can be divided into six layers. The microvascular network of the six individual layers is visualized, and the morphology and contrast images can be improved by using the segmentation method. This method has potential for earlier diagnosis and precise monitoring in retinal vascular diseases.

Paper Details

Date Published: 13 July 2015
PDF: 6 pages
J. Biomed. Opt. 20(7) 076003 doi: 10.1117/1.JBO.20.7.076003
Published in: Journal of Biomedical Optics Volume 20, Issue 7
Show Author Affiliations
Shenghai Huang, Wenzhou Medical College (China)
Beckman Laser Institute and Medical Clinic, Univ. of California, Irvine (United States)
Zhonglie Piao, Beckman Laser Institute and Medical Clinic, Univ. of California, Irvine (United Kingdom)
Jiang Zhu, Beckman Laser Institute and Medical Clinic, Univ. of California, Irvine (United States)
Fan Lu, Wenzhou Medical College (China)
Zhongping Chen, Wenzhou Medical Univ. (China)
Beckman Laser Institute and Medical Clinic, Univ. of California, Berkeley (United States)


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