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Journal of Biomedical Optics

Multiview Hilbert transformation for full-view photoacoustic computed tomography using a linear array
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Paper Abstract

Due to their low cost, hand-held convenience, wide selection of bandwidths, and ultrasound imaging capability, linear ultrasonic transducer arrays have been widely studied for photoacoustic computed tomography (PACT). As linear-array PACT suffers from a limited view, full-view imaging requires either the transducer or the object to be rotated. So far, both the central frequencies and bandwidth of linear transducer arrays applied in full-view PACT are low, limiting the spatial resolutions of the reconstructed images. Here, we present a multiview high-frequency PACT imaging system implemented with a commercial 40-MHz central frequency linear transducer array. By rotating the object through multiple angles with respect to the linear transducer array, we acquired full-view photoacoustic pressure measurements. Further, to quantify the unipolar initial pressures and overcome the limitations of the single-view Hilbert transformation, we developed a multiview Hilbert transformation method. The in-plane spatial resolution of this full-view linear-array PACT was quantified to be isotropically 60  μm within a 10×10  mm2 field of view. The system was demonstrated by imaging both a leaf skeleton and a zebrafish in vivo

Paper Details

Date Published: 25 June 2015
PDF: 6 pages
J. Biomed. Opt. 20(6) 066010 doi: 10.1117/1.JBO.20.6.066010
Published in: Journal of Biomedical Optics Volume 20, Issue 6
Show Author Affiliations
Guo Li, Washington Univ. in St. Louis (United States)
Lei Li, Washington Univ. in St. Louis (United States)
Liren Zhu, Washington Univ. in St. Louis (United States)
Jun Xia, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)

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