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Journal of Biomedical Optics • Open Access

Measurements of fundamental properties of homogeneous tissue phantoms

Paper Abstract

We present the optical measurement techniques used in human skin phantom studies. Their accuracy and the sources of errors in microscopic parameters’ estimation of the produced phantoms are described. We have produced optical phantoms for the purpose of simulating human skin tissue at the wavelength of 930 nm. Optical coherence tomography was used to measure the thickness and surface roughness and to detect the internal inhomogeneities. A more detailed study of phantom surface roughness was carried out with the optical profilometer. Reflectance, transmittance, and collimated transmittance of phantoms were measured using an integrating-sphere spectrometer setup. The scattering and absorption coefficients were calculated with the inverse adding-doubling method. The reduced scattering coefficient at 930 nm was found to be 1.57±0.14  mm−1 and the absorption was 0.22±0.03  mm−1. The retrieved optical properties of phantoms are in agreement with the data found in the literature for real human tissues.

Paper Details

Date Published: 17 April 2015
PDF: 10 pages
J. Biomed. Opt. 20(4) 045004 doi: 10.1117/1.JBO.20.4.045004
Published in: Journal of Biomedical Optics Volume 20, Issue 4
Show Author Affiliations
Maciej S. Wróbel, Gdansk Univ. of Technology (Poland)
Alexey P. Popov, Univ. of Oulu (Finland)
Alexander V. Bykov, Univ. of Oulu (Finland)
Matti Kinnunen, Univ. of Oulu (Finland)
Malgorzata Jędrzejewska-Szczerska, Gdansk Univ. of Technology (Poland)
Valery V. Tuchin, Univ. of Oulu (Finland)
N.G. Chernyshevsky Saratov State Univ. (Russian Federation)
Institute of Precise Mechanics and Control (Russian Federation)

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