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Journal of Biomedical Optics

Cherenkov luminescence imaging in transparent media and the imaging of thin or shallow sources
Author(s): Sergey Komarov; Dong Zhou; Yongjian Liu; Yuan-Chuan Tai
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Paper Abstract

In this work, we demonstrated the possibility of high spatial resolution Cherenkov luminescence imaging (CLI) for objects in transparent media. We also demonstrated the possibility of the CLI of thin opaque objects using optical transducers. Results demonstrate that submillimeter resolution CLI is achievable for beta-emitting radionuclides, including 76Br that emits positrons of very high energy. The imaging of beta-emitters through scintillation detectors exhibits lower resolution when compared to CLI of the same sources. The application of optical transducers for the CLI was demonstrated using plants labeled with 11CO2 and phantoms containing beta-emitters.

Paper Details

Date Published: 19 March 2015
PDF: 10 pages
J. Biomed. Opt. 20(3) 036011 doi: 10.1117/1.JBO.20.3.036011
Published in: Journal of Biomedical Optics Volume 20, Issue 3
Show Author Affiliations
Sergey Komarov, Washington Univ. School of Medicine in St. Louis (United States)
Dong Zhou, Washington Univ. School of Medicine in St. Louis (United States)
Yongjian Liu, Washington Univ. School of Medicine in St. Louis (United States)
Yuan-Chuan Tai, Washington Univ. in St. Louis (United States)

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