Share Email Print
cover

Journal of Biomedical Optics • Open Access

Transurethral light delivery for prostate photoacoustic imaging
Author(s): Muyinatu A. Lediju Bell; Xiaoyu Guo; Danny Y. Song; Emad M. Boctor

Paper Abstract

Photoacoustic imaging has broad clinical potential to enhance prostate cancer detection and treatment, yet it is challenged by the lack of minimally invasive, deeply penetrating light delivery methods that provide sufficient visualization of targets (e.g., tumors, contrast agents, brachytherapy seeds). We constructed a side-firing fiber prototype for transurethral photoacoustic imaging of prostates with a dual-array (linear and curvilinear) transrectal ultrasound probe. A method to calculate the surface area and, thereby, estimate the laser fluence at this fiber tip was derived, validated, applied to various design parameters, and used as an input to three-dimensional Monte Carlo simulations. Brachytherapy seeds implanted in phantom,

Paper Details

Date Published: 2 March 2015
PDF: 11 pages
J. Biomed. Opt. 20(3) 036002 doi: 10.1117/1.JBO.20.3.036002
Published in: Journal of Biomedical Optics Volume 20, Issue 3
Show Author Affiliations
Muyinatu A. Lediju Bell, Johns Hopkins Univ. (United States)
Johns Hopkins Univ. School of Medicine (United States)
Xiaoyu Guo, Johns Hopkins Univ. (United States)
Danny Y. Song, Johns Hopkins Univ. School of Medicine (United States)
Emad M. Boctor, Johns Hopkins Univ. (United States)
Johns Hopkins Univ. School of Medicine (United States)


© SPIE. Terms of Use
Back to Top