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Journal of Biomedical Optics • Open Access

Decoupled fluorescence Monte Carlo model for direct computation of fluorescence in turbid media
Author(s): Zhaoyang Luo; Yong Deng; Kan Wang; Lichao Lian; Xiaoquan Yang; Qingming Luo

Paper Abstract

We present a decoupled fluorescence Monte Carlo (dfMC) model for the direct computation of the fluorescence in turbid media. By decoupling the excitation-to-emission conversion and transport process of the fluorescence from the path probability density function and associating the corresponding parameters involving the fluorescence process with the weight function, the dfMC model employs the path histories of the excitation photons and the corresponding new weight function to directly calculate the fluorescence. We verify the model’s accuracy using phantom experiments and compare it with that of the perturbation fluorescence Monte Carlo model. The results indicate that the model is accurate for the direct fluorescence calculation and, thus, has great potential for application in fluorescence-based in vivo tomography.

Paper Details

Date Published: 3 February 2015
PDF: 10 pages
J. Biomed. Opt. 20(2) 025002 doi: 10.1117/1.JBO.20.2.025002
Published in: Journal of Biomedical Optics Volume 20, Issue 2
Show Author Affiliations
Zhaoyang Luo, Huazhong Univ. of Science and Technology (China)
Yong Deng, Huazhong Univ. of Science and Technology (China)
Kan Wang, Huazhong Univ. of Science and Technology (China)
Lichao Lian, Huazhong Univ. of Science and Technology (China)
Xiaoquan Yang, Huazhong Univ. of Science and Technology (China)
Qingming Luo, Huazhong Univ. of Science and Technology (China)


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