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Journal of Biomedical Optics

Adjunctive dental therapy via tooth plaque reduction and gingivitis treatment by blue light-emitting diodes tooth brushing
Author(s): Elina A. Genina; Vladimir A. Titorenko; Andrey V. Belikov; Alexey N. Bashkatov; Valery V. Tuchin
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Paper Abstract

The efficacy of blue light-emitting toothbrushes (B-LETBs) (405 to 420 nm, power density 2  mW/cm2) for reduction of dental plaques and gingival inflammation has been evaluated. Microbiological study has shown the multifactor therapeutic action of the B-LETBs on oral pathological microflora: in addition to partial mechanical removal of bacteria, photodynamic action suppresses them up to 97.5%. In the pilot clinical studies, subjects with mild to moderate gingivitis have been randomly divided into two groups: a treatment group that used the B-LETBs and a control group that used standard toothbrushes. Indices of plaque, gingival bleeding, and inflammation have been evaluated. A significant improvement of all dental indices in comparison with the baseline (by 59%, 66%, and 82% for plaque, gingival bleeding, and inflammation, respectively) has been found. The treatment group has demonstrated up to 50% improvement relative to the control group. We have proposed the B-LETBs to serve for prevention of gingivitis or as an alternative to conventional antibiotic treatment of this disease due to their effectiveness and the absence of drug side effects and bacterial resistance.

Paper Details

Date Published: 29 December 2015
PDF: 7 pages
J. Biomed. Opt. 20(12) 128004 doi: 10.1117/1.JBO.20.12.128004
Published in: Journal of Biomedical Optics Volume 20, Issue 12
Show Author Affiliations
Elina A. Genina, N.G. Chernyshevsky Saratov State Univ. (Russian Federation)
National Research Tomsk State Univ. (Russian Federation)
Vladimir A. Titorenko, Saratov State Medical Univ. (Russian Federation)
Andrey V. Belikov, ITMO Univ. (Russian Federation)
Alexey N. Bashkatov, N.G. Chernyshevsky Saratov State Univ. (Russian Federation)
National Research Tomsk State Univ. (Russian Federation)
Valery V. Tuchin, N.G. Chernyshevsky Saratov State Univ. (Russian Federation)
National Research Tomsk State Univ. (Russian Federation)
Institute of Precise Mechanics and Control (Russian Federation)


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