Share Email Print
cover

Journal of Biomedical Optics

Tri-band spectroscopic optical coherence tomography based on optical parametric amplification for lipid and vessel visualization
Author(s): Luoqin Yu; Jiqiang Kang; Chandra Jinata; Xie Wang; Xiaoming Wei; Kin Tak Chan; Nikki P. Lee; Kenneth K. Y. Wong
Format Member Price Non-Member Price
PDF $20.00 $25.00

Paper Abstract

A tri-band spectroscopic optical coherence tomography (SOCT) system has been implemented for visualization of lipid and blood vessel distribution. The tri-band swept source, which covers output spectrum in 1.3, 1.5, and 1.6  μm wavelength windows, is based on a dual-band Fourier domain mode-locked laser and a fiber optical parametric amplifier. This tri-band SOCT can further differentiate materials, e.g., lipid and artery, qualitatively by contrasting attenuation coefficients difference within any two of these bands. Furthermore, ex vivo imaging of both porcine artery with artificial lipid plaque phantom and mice with coronary artery disease were demonstrated to showcase the capability of our SOCT.

Paper Details

Date Published: 16 December 2015
PDF: 8 pages
J. Biomed. Opt. 20(12) 126006 doi: 10.1117/1.JBO.20.12.126006
Published in: Journal of Biomedical Optics Volume 20, Issue 12
Show Author Affiliations
Luoqin Yu, The Univ. of Hong Kong (Hong Kong, China)
Jiqiang Kang, The Univ. of Hong Kong (Hong Kong, China)
Chandra Jinata, The Univ. of Hong Kong (Hong Kong, China)
Xie Wang, The Univ. of Hong Kong (Hong Kong, China)
Xiaoming Wei, The Univ. of Hong Kong (Hong Kong, China)
Kin Tak Chan, The Univ. of Hong Kong (Hong Kong, China)
Nikki P. Lee, The Univ. of Hong Kong (Hong Kong, China)
Kenneth K. Y. Wong, The Univ. of Hong Kong (Hong Kong, China)


© SPIE. Terms of Use
Back to Top