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Journal of Biomedical Optics

Learning curve and interobserver variance in quantification of the optical coherence tomography attenuation coefficient
Author(s): Ronni Wessels; Daniel Martijn de Bruin; Dirk J. Faber; Joyce Sanders; Andrew D. Vincent; Marc van Beurden; Ton G. van Leeuwen; Theo J.M. Ruers
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Paper Abstract

The learning curve and interobserver variance of attenuation coefficient (μOCT) determination from optical coherence tomography (OCT) images were quantified. The μOCT of normal and diseased vulvar tissues was determined at five time points by three novice students and three OCT experts who reached consensus for reference. Students received feedback between time points. Eventually, variance in μOCT was smaller in images of diseased tissue than in images of normal vulvar tissue. The difference between the consensus and student μOCT values was larger for smaller values of μOCT. We conclude that routine μOCT determination for tissue classification does not require extensive training.

Paper Details

Date Published: 14 December 2015
PDF: 8 pages
J. Biomed. Opt. 20(12) 121313 doi: 10.1117/1.JBO.20.12.121313
Published in: Journal of Biomedical Optics Volume 20, Issue 12
Show Author Affiliations
Ronni Wessels, Het Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis (The Netherlands)
Daniel Martijn de Bruin, Academisch Medisch Centrum (Netherlands)
Dirk J. Faber, Academisch Medisch Centrum (The Netherlands)
Joyce Sanders, Het Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis (The Netherlands)
Andrew D. Vincent, Het Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis (The Netherlands)
Marc van Beurden, Het Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis (The Netherlands)
Ton G. van Leeuwen, Academisch Medisch Centrum (The Netherlands)
Theo J.M. Ruers, Het Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis (The Netherlands)
Univ. Twente (The Netherlands)


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