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Journal of Biomedical Optics • Open Access

Mechanically switchable solid inhomogeneous phantom for performance tests in diffuse imaging and spectroscopy

Paper Abstract

A mechanically switchable solid inhomogeneous phantom simulating localized absorption changes was developed and characterized. The homogeneous host phantom was made of epoxy resin with black toner and titanium dioxide particles added as absorbing and scattering components, respectively. A cylindrical rod, movable along a hole in the block and made of the same material, has a black polyvinyl chloride cylinder embedded in its center. By varying the volume and position of the black inclusion, absorption perturbations can be generated over a large range of magnitudes. The phantom has been characterized by various time-domain diffuse optics instruments in terms of absorption and scattering spectra, transmittance images, and reflectance contrast. Addressing a major application of the phantom for performance characterization for functional near-infrared spectroscopy of the brain, the contrast was measured in reflectance mode while black cylinders of volumes from ≈20  mm3 to ≈270  mm3 were moved in lateral and depth directions, respectively. The new type of solid inhomogeneous phantom is expected to become a useful tool for routine quality check of clinical instruments or implementation of industrial standards provided an experimental characterization of the phantom is performed in advance.

Paper Details

Date Published: 28 July 2015
PDF: 10 pages
J. Biomed. Opt. 20(12) 121304 doi: 10.1117/1.JBO.20.12.121304
Published in: Journal of Biomedical Optics Volume 20, Issue 12
Show Author Affiliations
Antonio Pifferi, Politecnico di Milano (Italy)
Alessandro Torricelli, Politecnico di Milano (Italy)
Rinaldo Cubeddu, Politecnico di Milano (Italy)
CNR-Istituto di Fotonica e Nanotecnologie (Italy)
Giovanna Quarto, Politecnico di Milano (Italy)
Rebecca Re, Politecnico di Milano (Italy)
Sanathana K. V. Sekar, Politecnico di Milano (Italy)
Lorenzo Spinelli, CNR-Istituto di Fotonica e Nanotecnologie (Italy)
Andrea Farina, CNR-Istituto di Fotonica e Nanotecnologie (Italy)
Fabrizio Martelli, Univ. degli Studi di Firenze (Italy)
Heidrun Wabnitz, Physikalisch-Technische Bundesanstalt (Germany)

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