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Journal of Biomedical Optics

Imaginary part-based correlation mapping optical coherence tomography for imaging of blood vessels <italic<in vivo</italic<
Author(s): Chaoliang Chen; Weisong Shi; Wanrong Gao
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Paper Abstract

We present an imaginary part-based correlation mapping optical coherence tomography (IMcmOCT) technique for <italic<in vivo</italic< blood vessels imaging. In the conventional correlation mapping optical coherence tomography (cmOCT) method, two adjacent frames of intensity-based structural images are correlated to extract blood flow information and the size of correlation window has to be increased to improve the signal-to-noise ratio of microcirculation maps, which may cause image blur and miss the small blood vessels. In the IMcmOCT method, the imaginary part of a depth-resolved complex analytic signal in two adjacent B-scans is correlated to reconstruct microcirculation maps. Both phantom and <italic<in vivo</italic< experiments were implemented to demonstrate that the proposed method can provide improved sensitivity for extracting blood flow information in small vessels.

Paper Details

Date Published: 30 November 2015
PDF: 8 pages
J. Biomed. Opt. 20(11) 116009 doi: 10.1117/1.JBO.20.11.116009
Published in: Journal of Biomedical Optics Volume 20, Issue 11
Show Author Affiliations
Chaoliang Chen, Nanjing Univ. of Science and Technology (China)
Weisong Shi, Nanjing Univ. of Science and Technology (China)
Wanrong Gao, Nanjing Univ. of Science and Technology (China)


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