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Journal of Biomedical Optics

Randomized <italic<in vivo</italic< evaluation of photodynamic antimicrobial chemotherapy on deciduous carious dentin
Author(s): Carolina Steiner-Oliveira; Priscila Larcher Longo; Ana Cecília Corrêa Aranha; Karen Müller Ramalho; Marcia Pinto Alves Mayer; Carlos de Paula Eduardo
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Paper Abstract

The aim of this randomized <italic<in vivo</italic< study was to compare antimicrobial chemotherapies in primary carious dentin. Thirty-two participants ages 5 to 7 years underwent partial caries removal from deep carious dentin lesions in primary molars and were subsequently divided into three groups: control [chlorhexidine and resin-modified glass ionomer cement (RMGIC)], LEDTB [photodynamic antimicrobial chemotherapy (PACT) with light-emitting diode associated with toluidine blue solution and RMGIC], and LMB [PACT with laser associated with methylene blue solution and RMGIC]. The participants were submitted to initial clinical and radiographic examinations. Demographic features and biofilm, gingival, and DMFT/DMFS indexes were evaluated, in addition to clinical and radiographic followups at 6 and 12 months after treatments. Carious dentin was collected before and after each treatment, and the number of <italic<Streptococcus mutans, Streptococcus sobrinus, Lactobacillus casei, Fusobacterium nucleatum, Atopobium rimae</italic<, and total bacteria was established by quantitative polymerase chain reaction. No signs of pain or restoration failure were observed. All therapies were effective in reducing the number of microorganisms, except for <italic<S. sobrinus</italic<. No statistical differences were observed among the protocols used. All therapies may be considered as effective modern approaches to minimal intervention for the management of deep primary caries treatment.

Paper Details

Date Published: 26 October 2015
PDF: 7 pages
J. Biomed. Opt. 20(10) 108003 doi: 10.1117/1.JBO.20.10.108003
Published in: Journal of Biomedical Optics Volume 20, Issue 10
Show Author Affiliations
Carolina Steiner-Oliveira, Univ. Estadual de Campinas (Brazil)
Priscila Larcher Longo, Univ. de São Paulo (Brazil)
Ana Cecília Corrêa Aranha, Univ. de São Paulo (Brazil)
Karen Müller Ramalho, Univ. de São Paulo (Brazil)
Marcia Pinto Alves Mayer, Univ. de São Paulo (Brazil)
Carlos de Paula Eduardo, Univ. de São Paulo (Brazil)


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