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Journal of Biomedical Optics

Swept source optical coherence tomography Gabor fusion splicing technique for microscopy of thick samples using a deformable mirror
Author(s): Christopher Costa; Adrian Bradu; John Rogers; Pauline Phelan; Adrian Podoleanu
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Paper Abstract

We present a swept source optical coherence tomography (OCT) system at 1060 nm equipped with a wavefront sensor at 830 nm and a deformable mirror in a closed-loop adaptive optics (AO) system. Due to the AO correction, the confocal profile of the interface optics becomes narrower than the OCT axial range, restricting the part of the B-scan (cross section) with good contrast. By actuating on the deformable mirror, the depth of the focus is changed and the system is used to demonstrate Gabor filtering in order to produce B-scan OCT images with enhanced sensitivity throughout the axial range from a Drosophila larvae. The focus adjustment is achieved by manipulating the curvature of the deformable mirror between two user-defined limits. Particularities of controlling the focus for Gabor filtering using the deformable mirror are presented.

Paper Details

Date Published: 14 January 2015
PDF: 10 pages
J. Biomed. Opt. 20(1) 016012 doi: 10.1117/1.JBO.20.1.016012
Published in: Journal of Biomedical Optics Volume 20, Issue 1
Show Author Affiliations
Christopher Costa, Univ. of Kent (United Kingdom)
Adrian Bradu, Univ. of Kent (United Kingdom)
John Rogers, Univ. of Kent (United Kingdom)
Pauline Phelan, Univ. of Kent (United Kingdom)
Adrian Podoleanu, Univ. of Kent (United Kingdom)

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