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Journal of Biomedical Optics

Three-dimensional segmentation and reconstruction of the retinal vasculature from spectral-domain optical coherence tomography
Author(s): Pedro Guimarães; Pedro Rodrigues; Dirce Celorico; Pedro Serranho; Rui Bernardes
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Paper Abstract

We reconstruct the three-dimensional shape and location of the retinal vascular network from commercial spectral-domain (SD) optical coherence tomography (OCT) data. The two-dimensional location of retinal vascular network on the eye fundus is obtained through support vector machines classification of properly defined fundus images from OCT data, taking advantage of the fact that on standard SD-OCT, the incident light beam is absorbed by hemoglobin, creating a shadow on the OCT signal below each perfused vessel. The depth-wise location of the vessel is obtained as the beginning of the shadow. The classification of crossovers and bifurcations within the vascular network is also addressed. We illustrate the feasibility of the method in terms of vessel caliber estimation and the accuracy of bifurcations and crossovers classification.

Paper Details

Date Published: 7 January 2015
PDF: 11 pages
J. Biomed. Opt. 20(1) 016006 doi: 10.1117/1.JBO.20.1.016006
Published in: Journal of Biomedical Optics Volume 20, Issue 1
Show Author Affiliations
Pedro Guimarães, Univ. de Coimbra (Portugal)
Univ. degli Studi di Padova (Italy)
Pedro Rodrigues, Association for Innovation and Biomedical Research on Light and Image (Portugal)
Univ. de Coimbra (Portugal)
Dirce Celorico, Association for Innovation and Biomedical Research on Light and Image (Portugal)
Pedro Serranho, Univ. de Coimbra (Portugal)
Univ. Aberta (Portugal)
Rui Bernardes, Univ. de Coimbra (Portugal)


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