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Journal of Biomedical Optics • Open Access

Three-dimensional illumination procedure for photodynamic therapy of dermatology

Paper Abstract

Light dosimetry is an important parameter that affects the efficacy of photodynamic therapy (PDT). However, the irregular morphologies of lesions complicate lesion segmentation and light irradiance adjustment. Therefore, this study developed an illumination demo system comprising a camera, a digital projector, and a computing unit to solve these problems. A three-dimensional model of a lesion was reconstructed using the developed system. Hierarchical segmentation was achieved with the superpixel algorithm. The expected light dosimetry on the targeted lesion was achieved with the proposed illumination procedure. Accurate control and optimization of light delivery can improve the efficacy of PDT.

Paper Details

Date Published: 9 September 2014
PDF: 7 pages
J. Biomed. Opt. 19(9) 098003 doi: 10.1117/1.JBO.19.9.098003
Published in: Journal of Biomedical Optics Volume 19, Issue 9
Show Author Affiliations
Xiao-Ming Hu, Beijing Institute of Technology (China)
Feng-juan Zhang, Beijing Institute of Technology (China)
Fei Dong, Beijing Institute of Technology (China)
Ya Zhou, Beijing Institute of Technology (China)

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