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Journal of Biomedical Optics

Investigating femtosecond-laser-induced two-photon photoacoustic generation
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Paper Abstract

We investigated two-photon absorption-based photoacoustic generation and compared it with corresponding photoluminescence emission. Experimental results revealed expected quadratic dependences on the incident optical fluence in both photoacoustic and photoluminescence processes. We also investigated the influence of optical scattering on the generation of two-photon photoacoustic and photoluminescence signals and found that photoacoustic signals attenuated more slowly than photoluminescence signals when the optical scattering coefficient was increased, which was attributed to a weaker ultrasonic attenuation than that the optical attenuation in the scattering medium. Finally, we showed three-dimensional two-photon photoacoustic imaging.

Paper Details

Date Published: 1 August 2014
PDF: 6 pages
J. Biomed. Opt. 19(8) 085001 doi: 10.1117/1.JBO.19.8.085001
Published in: Journal of Biomedical Optics Volume 19, Issue 8
Show Author Affiliations
Ben E. Urban, Northwestern Univ. (United States)
Ji Yi, Northwestern Univ. (United States)
Vladislav Yakovlev, Texas A&M Univ. (United States)
Hao F. Zhang, Northwestern Univ. (United States)

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