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Journal of Biomedical Optics • Open Access

Real-time high-resolution measurement of collagen alignment in dynamically loaded soft tissue
Author(s): Timothy York; Lindsey Kahan; Spencer P. Lake; Viktor Gruev

Paper Abstract

A technique for creating maps of the direction and strength of fiber alignment in collagenous soft tissues is presented. The method uses a division of focal plane polarimeter to measure circularly polarized light transmitted through the tissue. The architecture of the sensor allows measurement of the retardance and fiber alignment at the full frame rate of the sensor without any moving optics. The technique compares favorably to the standard method of using a rotating polarizer. How the new technique enables real-time capture of the full angular spread of fiber alignment and retardance under various cyclic loading conditions is illustrated.

Paper Details

Date Published: 27 June 2014
PDF: 6 pages
J. Biomed. Opt. 19(6) 066011 doi: 10.1117/1.JBO.19.6.066011
Published in: Journal of Biomedical Optics Volume 19, Issue 6
Show Author Affiliations
Timothy York, Washington Univ. in St. Louis (United States)
Lindsey Kahan, Washington Univ. in St. Louis (United States)
Spencer P. Lake, Washington Univ. in St. Louis (United States)
Viktor Gruev, Washington Univ. in St. Louis (United States)

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