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Journal of Biomedical Optics • Open Access

The Toast++ software suite for forward and inverse modeling in optical tomography
Author(s): Martin Schweiger; Simon R. Arridge

Paper Abstract

We present the Toast++ open-source software environment for solving the forward and inverse problems in diffuse optical tomography (DOT). The software suite consists of a set of libraries to simulate near-infrared light propagation in highly scattering media with complex boundaries and heterogeneous internal parameter distribution, based on a finite-element solver. Steady-state, time- and frequency-domain data acquisition systems can be modeled. The forward solver is implemented in C++ and supports performance acceleration with parallelization for shared and distributed memory architectures, as well as graphics processing computation. Building on the numerical forward solver, Toast++ contains model-based iterative inverse solvers for reconstructing the volume distribution of absorption and scattering parameters from boundary measurements of light transmission. A range of regularization methods are provided, including the possibility of incorporating prior knowledge of internal structure. The user can link to the Toast++ libraries either directly to compile application programs for DOT, or make use of the included MATLAB and PYTHON bindings to generate script-based solutions. This approach allows rapid prototyping and provides a rich toolset in both environments for debugging, testing, and visualization.

Paper Details

Date Published: 29 April 2014
PDF: 16 pages
J. Biomed. Opt. 19(4) 040801 doi: 10.1117/1.JBO.19.4.040801
Published in: Journal of Biomedical Optics Volume 19, Issue 4
Show Author Affiliations
Martin Schweiger, Univ. College London (United Kingdom)
Simon R. Arridge, Univ. College London (United Kingdom)


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