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Journal of Biomedical Optics

In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography
Author(s): Lidek Chou; Andriy Batchinsky; Slava Belenkiy; Joseph C. Jing; Tirunelvil Ramalingam; Matthew Brenner; Zhongping Chen
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Paper Abstract

We report on the feasibility of using long-range swept-source optical coherence tomography (OCT) to detect airway changes following smoke inhalation in a sheep model. The long-range OCT system (with axial imaging range of 25 mm) and probe are capable of rapidly obtaining a series of high-resolution full cross-sectional images and three-dimensional reconstructions covering 20-cm length of tracheal and bronchial airways with airway diameter up to 25 mm, regardless of the position of the probe within the airway lumen. Measurements of airway thickness were performed at baseline and postinjury to show mucosal thickness changes following smoke inhalation.

Paper Details

Date Published: 24 March 2014
PDF: 7 pages
J. Biomed. Opt. 19(3) 036018 doi: 10.1117/1.JBO.19.3.036018
Published in: Journal of Biomedical Optics Volume 19, Issue 3
Show Author Affiliations
Lidek Chou, Beckman Laser Institute and Medical Clinic (United States)
Andriy Batchinsky, U.S. Army Institute of Surgical Research (United States)
Slava Belenkiy, U.S. Army Institute of Surgical Research (United States)
Joseph C. Jing, Univ. of California, Irvine (United States)
Tirunelvil Ramalingam, Oct Medical Imaging, Inc. (United States)
Matthew Brenner, Univ. of California, Irvine (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)


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