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Journal of Biomedical Optics

Compressed sensing based virtual-detector photoacoustic microscopy in vivo
Author(s): Jing Meng; Chengbo Liu; Jiaxiang Zheng; Riqiang Lin; Liang Song
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Paper Abstract

Photoacoustic microscopy (PAM) is becoming a vital tool for various biomedical studies, including functional and molecular imaging of cancer. However, due to the use of a focused ultrasonic transducer for photoacoustic detection, the image quality of conventional PAM degrades rapidly away from the ultrasonic focal zone. To improve the image quality of PAM for out-of-focus regions, we have developed compressed sensing based virtual-detector photoacoustic microscopy (CS-PAM). Through phantom and in vivo experiments, it has been demonstrated that CS-PAM can effectively extend the depth of focus of PAM, and thus may greatly expand its potential biomedical applications.

Paper Details

Date Published: 5 March 2014
PDF: 6 pages
J. Biomed. Opt. 19(3) 036003 doi: 10.1117/1.JBO.19.3.036003
Published in: Journal of Biomedical Optics Volume 19, Issue 3
Show Author Affiliations
Jing Meng, Qufu Normal Univ. (China)
Chengbo Liu, Shenzhen Institute of Advanced Technology (China)
Jiaxiang Zheng, Shenzhen Institute of Advanced Technology (China)
Riqiang Lin, Shenzhen Institute of Advanced Technology (China)
Liang Song, Shenzhen Institute of Advanced Technology (China)


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