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Journal of Biomedical Optics • Open Access

Contact pressure–aided spectroscopy
Author(s): Maksimilijan Bregar; Miran Bürmen; Uros Aljancic; Blaž Cugmas; Franjo Pernuš; Boštjan Likar

Paper Abstract

Contact pressure induced by manually operated fiber optic probes can significantly affect the optical properties of the studied tissue. If the contact pressure and the changes in optical properties are measured properly, then the complementary information can be used to obtain additional insight into the tissue physiology. However, as reliable assessment of the contact pressure in the existing diffuse reflectance setups is difficult, the impact of contact pressure is usually neglected or considered as a source of errors. We introduce a measurement system for controlled application of contact pressure and for the acquisition of diffuse reflectance spectra, which is suitable for in vivo studies and for overcoming the limitations of the existing measurement setups. A spectral-contact-pressure plane is proposed to present the combined information, highlighting the unique tissue response to the applied pressure.

Paper Details

Date Published: 21 February 2014
PDF: 4 pages
J. Biomed. Opt. 19(2) 020501 doi: 10.1117/1.JBO.19.2.020501
Published in: Journal of Biomedical Optics Volume 19, Issue 2
Show Author Affiliations
Maksimilijan Bregar, Univ. of Ljubljana (Slovenia)
Miran Bürmen, Univ. of Ljubljana (Slovenia)
Uros Aljancic, Univ. of Ljubljana (Slovenia)
Blaž Cugmas, Univ. of Ljubljana (Slovenia)
Franjo Pernuš, Univ. of Ljubljana (Slovenia)
Boštjan Likar, Univ. of Ljubljana (Slovenia)

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