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Journal of Biomedical Optics • Open Access

Confocal microlaparoscope for imaging the fallopian tube
Author(s): Tzu-Yu Wu; Andrew R. Rouse; Setsuko K. Chambers; Kenneth D. Hatch; Arthur F. Gmitro

Paper Abstract

Recent evidence suggests that ovarian cancer can originate in the fallopian tube. Unlike many other cancers, poor access to the ovary and fallopian tubes has limited the ability to study the progression of this deadly disease and to diagnosis it during the early stage when it is most amenable to therapy. A rigid confocal microlaparoscope system designed to image the epithelial surface of the ovary <italic<in vivo</italic< was previously reported. A new confocal microlaparoscope with an articulating distal tip has been developed to enable <italic<in vivo</italic< access to human fallopian tubes. The new microlaparoscope is compatible with 5-mm trocars and includes a 2.2-mm-diameter articulating distal tip consisting of a bare fiber bundle and an automated dye delivery system for fluorescence confocal imaging. This small articulating device should enable the confocal microlaparoscope to image early stage ovarian cancer arising inside the fallopian tube. <italic<Ex vivo</italic< images of animal tissue and human fallopian tube using the new articulating device are presented along with <italic<in vivo</italic< imaging results using the rigid confocal microlaparoscope system.

Paper Details

Date Published: 20 November 2014
PDF: 6 pages
J. Biomed. Opt. 19(11) 116010 doi: 10.1117/1.JBO.19.11.116010
Published in: Journal of Biomedical Optics Volume 19, Issue 11
Show Author Affiliations
Tzu-Yu Wu, College of Optical Sciences, The Univ. of Arizona (United States)
Univ. of Arizona (United States)
Andrew R. Rouse, The Univ. of Arizona (United States)
The Univ. of Arizona (United States)
The Univ. of Arizona Cancer Ctr. (United States)
Setsuko K. Chambers, The Univ. of Arizona (United States)
Kenneth D. Hatch, The Univ. of Arizona (United States)
Arthur F. Gmitro, The Univ. of Arizona (United States)


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