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Journal of Biomedical Optics • Open Access

Clinical Raman measurements under special ambient lighting illumination
Author(s): Jianhua Zhao; Michael A. Short; Thomas A. Braun; Harvey Lui; David I. McLean; Haishan Zeng

Paper Abstract

One challenge in facing the application of biomedical Raman spectroscopy is that the Raman signal is acquired in a dark operation room. It is inconvenient for both the operator and the patient because it is difficult for the operator to accurately and precisely locate the target in the dark environment, and the patient feels uncomfortable in such a setting. In this note, we propose a method to implement biomedical Raman measurement with an illumination source, by multiple filtering of the illumination and the collection optics. Experimental results are demonstrated on skin Raman measurement under 785-nm excitation.

Paper Details

Date Published: 17 June 2014
PDF: 4 pages
J. Biomed. Opt. 19(11) 111609 doi: 10.1117/1.JBO.19.11.111609
Published in: Journal of Biomedical Optics Volume 19, Issue 11
Show Author Affiliations
Jianhua Zhao, The BC Cancer Agency Research Ctr. (Canada)
The Univ. of British Columbia and Vancouver Coastal Health Research Institute (Canada)
Michael A. Short, The BC Cancer Agency Research Ctr. (Canada)
Thomas A. Braun, Verisante Technology, Inc. (Canada)
Harvey Lui, The Univ. of British Columbia (Canada)
David I. McLean, The Univ. of British Columbia (Canada)
Haishan Zeng, The BC Cancer Agency Research Ctr. (Canada)
The Univ. of British Columbia and Vancouver Coastal Health Research Institute (Canada)


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