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Journal of Biomedical Optics

Implantable photonic devices for improved medical treatments
Author(s): Victor Sheinman; Arkady Rudnitsky; Rakhmanbek Toichuev; Abdyrakhman Eshiev; Svetlana Abdullaeva; Talantbek Egemkulov; Zeev Zalevsky
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Paper Abstract

An evolving area of biomedical research is related to the creation of implantable units that provide various possibilities for imaging, measurement, and the monitoring of a wide range of diseases and intrabody phototherapy. The units can be autonomic or built-in in some kind of clinically applicable implants. Because of specific working conditions in the live body, such implants must have a number of features requiring further development. This topic can cause wide interest among developers of optical, mechanical, and electronic solutions in biomedicine. We introduce preliminary clinical trials obtained with an implantable pill and devices that we have developed. The pill and devices are capable of applying in-body phototherapy, low-level laser therapy, blue light (450 nm) for sterilization, and controlled injection of chemicals. The pill is also capable of communicating with an external control box, including the transmission of images from inside the patient’s body. In this work, our pill was utilized for illumination of the sinus-carotid zone in dog and red light influence on arterial pressure and heart rate was demonstrated. Intrabody liver tissue laser ablation and nanoparticle-assisted laser ablation was investigated. Sterilization effect of intrabody blue light illumination was applied during a maxillofacial phlegmon treatment.

Paper Details

Date Published: 3 October 2014
PDF: 8 pages
J. Biomed. Opt. 19(10) 108001 doi: 10.1117/1.JBO.19.10.108001
Published in: Journal of Biomedical Optics Volume 19, Issue 10
Show Author Affiliations
Victor Sheinman, Bar-Ilan Univ. (Israel)
Arkady Rudnitsky, Bar-Ilan Univ. (Israel)
Rakhmanbek Toichuev, National Academy of Sciences of Kyrgyzstan (Kyrgyzstan)
Abdyrakhman Eshiev, Regional Clinical Hospital of Osh (Kyrgyzstan)
Svetlana Abdullaeva, Regional Clinical Hospital of Osh (Kyrgyzstan)
Talantbek Egemkulov, Regional Clinical Hospital of Osh (Kyrgyz Republic)
Zeev Zalevsky, Bar-Ilan Univ. (Israel)

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