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Journal of Biomedical Optics • Open Access

Effect of probe geometry and optical properties on the sampling depth for diffuse reflectance spectroscopy

Paper Abstract

The sampling depth of light for diffuse reflectance spectroscopy is analyzed both experimentally and computationally. A Monte Carlo (MC) model was used to investigate the effect of optical properties and probe geometry on sampling depth. MC model estimates of sampling depth show an excellent agreement with experimental measurements over a wide range of optical properties and probe geometries. The MC data are used to define a mathematical expression for sampling depth that is expressed in terms of optical properties and probe geometry parameters.

Paper Details

Date Published: 27 October 2014
PDF: 6 pages
J. Biomed. Opt. 19(10) 107002 doi: 10.1117/1.JBO.19.10.107002
Published in: Journal of Biomedical Optics Volume 19, Issue 10
Show Author Affiliations
Ricky Hennessy, The Univ. of Texas at Austin (United States)
Will Goth, The Univ. of Texas at Austin (United States)
Manu Sharma, The Univ. of Texas at Austin (United States)
Mia K. Markey, The Univ. of Texas at Austin (United States)
The Univ. of Texas MD Anderson Cancer Ctr. (United States)
James W. Tunnell, The Univ. of Texas at Austin (United States)


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