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Journal of Biomedical Optics

Heat profiles of laser-irradiated nails
Author(s): Uwe Paasch; Pietro Nenoff; Anna-Theresa Seitz; Justinus A. Wagner; Michael Kendler; Jan C. Simon; Sonja Grunewald
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Paper Abstract

Onychomycosis is a worldwide problem with no tendency for self-healing, and existing systemic treatments achieve disease-free nails in only 35 to 76% of cases. Recently, treatment of nail fungus with a near-infrared laser has been introduced. It is assumed that fungal eradication is mediated by local heat. To investigate if laser treatment has the potential to eradicate fungal hyphae and arthrospores, laser heat application and propagation needs to be studied in detail. This study aimed to measure nail temperatures using real-time videothermography during laser irradiation. Treatment was performed using 808- and 980-nm linear scanning diode lasers developed for hair removal, enabling contact-free homogeneous irradiation of a human nail plate in one pass. Average and peak temperatures increased pass by pass, while the laser beam moved along the nail plates. The achieved mean peak temperatures (808 nm: 74.1 to 112.4°C, 980 nm: 45.8 to 53.5°C), as well as the elevation of average temperatures (808 nm: 29.5 to 38.2°C, 980 nm: 27.1 to 32.6°C) were associated with pain that was equivalent to that of hair removal procedures and was not significantly different for various wavelengths. The linear scanning laser devices provide the benefits of contact-free homogeneous heating of the human nail while ensuring adequate temperature rises.

Paper Details

Date Published: 9 January 2014
PDF: 9 pages
J. Biomed. Opt. 19(1) 018001 doi: 10.1117/1.JBO.19.1.018001
Published in: Journal of Biomedical Optics Volume 19, Issue 1
Show Author Affiliations
Uwe Paasch, Universitätsklinikum Leipzig (Germany)
Pietro Nenoff, Labor für medizinische Mikrobiologie (Germany)
Anna-Theresa Seitz, Universitätsklinikum Leipzig (Germany)
Justinus A. Wagner, Universitätsklinikum Leipzig (Germany)
Michael Kendler, Universitätsklinikum Leipzig (Germany)
Jan C. Simon, Universitätsklinikum Leipzig (Germany)
Sonja Grunewald, Universitätsklinikum Leipzig (Germany)

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