Share Email Print

Journal of Biomedical Optics

Detection of melamine on fractals of unmodified gold nanoparticles by surface-enhanced Raman scattering
Author(s): Pradip Kumar Roy; Yi-Fan Huang; Surojit Chattopadhyay
Format Member Price Non-Member Price
PDF $20.00 $25.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

A simple way of detecting melamine in raw milk is demonstrated via surface-enhanced Raman spectroscopy (SERS) using fractals of bare and nonfunctionalized ∼30  nm gold nanoparticles (AuNP) distributed on a solid support. The technique demonstrates the formation of AuNP fractals, from a random distribution, upon exposure to melamine, that enhance the Raman scattering cross-section to enable detection by SERS. The agglomeration, which is pronounced at higher melamine concentrations, is demonstrated directly through imaging, and the red-shift of the plasmon absorption peak of the AuNP fractal away from 530 nm by finite difference time domain (FDTD) calculations. The agglomeration results in a strong plasmon field, shown by FDTD, over the interparticle sites that enhances the Raman scattering cross-section of melamine and ensures unambiguous detection. Limit of detection of 100 ppb could be achieved reproducibly.

Paper Details

Date Published: 10 June 2013
PDF: 12 pages
J. Biomed. Opt. 19(1) 011002 doi: 10.1117/1.JBO.19.1.011002
Published in: Journal of Biomedical Optics Volume 19, Issue 1
Show Author Affiliations
Pradip Kumar Roy, National Yang-Ming Univ. (Taiwan)
Yi-Fan Huang, National Yang-Ming Univ. (Taiwan)
Surojit Chattopadhyay, National Yang-Ming Univ. (Taiwan)

© SPIE. Terms of Use
Back to Top