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Journal of Biomedical Optics • Open Access

Laser speckle contrast imaging: theoretical and practical limitations

Paper Abstract

When laser light illuminates a diffuse object, it produces a random interference effect known as a speckle pattern. If there is movement in the object, the speckles fluctuate in intensity. These fluctuations can provide information about the movement. A simple way of accessing this information is to image the speckle pattern with an exposure time longer than the shortest speckle fluctuation time scale—the fluctuations cause a blurring of the speckle, leading to a reduction in the local speckle contrast. Thus, velocity distributions are coded as speckle contrast variations. The same information can be obtained by using the Doppler effect, but producing a two-dimensional Doppler map requires either scanning of the laser beam or imaging with a high-speed camera: laser speckle contrast imaging (LSCI) avoids the need to scan and can be performed with a normal CCD- or CMOS-camera. LSCI is used primarily to map flow systems, especially blood flow. The development of LSCI is reviewed and its limitations and problems are investigated.

Paper Details

Date Published: 27 June 2013
PDF: 10 pages
J. Biomed. Opt. 18(6) 066018 doi: 10.1117/1.JBO.18.6.066018
Published in: Journal of Biomedical Optics Volume 18, Issue 6
Show Author Affiliations
David Briers, Kingston Univ. (United Kingdom)
Donald D. Duncan, Portland State Univ. (United States)
Evan R. Hirst, Callaghan Innovation (New Zealand)
Sean J. Kirkpatrick, Michigan Technological Univ. (United States)
Marcus Larsson, Linköping Univ. (Sweden)
Wiendelt Steenbergen, Univ. Twente (Netherlands)
Tomas Stromberg, Linköping Univ (Sweden)
Oliver B. Thompson, Callaghan Innovation (New Zealand)

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